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Drug use evaluation(DUE) is a system for assuring the quality of drug use in patient care. It was performed on ofloxacin for the purpose of presenting the more reasonable drug therapy. Fifty eight cased of patients, who had been treated with ofloxacin in Korea University Kuro Hospital form September 1. 1994 to April 30. 1995, were reviewed retrospectively. The applicated criteria for ofloxacin was "Criteria for Drug Use Evaluation" established by ASHP report 1993. The results of the analysis show that 34 cases (59%) were met with the criteria for the justification of use, while 24 cases (41%) were not. In critical indicators, several criteria including culture & sensitivity test, vital sing, WBC monitoring and urinalysis were relatively well performed showing the accepted level above 70%, while serum creatinine monitoring and administration time were infrequently performed with low accepted level. Accepted level of ofloxacin was relatively high, while notice about drug interaction and complications were low, which indicate that medication were being performed under the insufficient information about each drug in clinic. The cased met with all criteria were 13 cases (22%), all included of which were in internal medicine. From the results, it could be concluded that medical staff should get the more information on general area of antimicrobial agents include complication, duration of therapy and characteristics of each drugs.
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